Michael Young's sacrifice fly in the 15th inning gave the American League a 4-3 victory over the National League in the longest All-Star game ever played.
Young's shot to right field scored Justin Morneau to bring to an end a marathon game at Yankee Stadium.
Brad Lidge (0-1) - the last remaining pitcher on the NL side - loaded the bases in the 15th before Young lifted a lazy fly to right.
Corey Hart settled under the ball and fired to the plate, but the throw was slightly up the first base line, allowing Morneau to slide in safely.
The All-Star festivities have been used as one big goodbye to Yankee Stadium, which has a date with a wrecking ball in November.
Many of the players voiced their joy at being named to the game in the final season of the hallowed stadium, and they certainly played like it.
The game tied the record for longest Midsummer Classic in terms of innings and surpassed the record in terms of total time.
Records were set across the board, as the teams combined for the most total stolen bases in a Midsummer Classic - seven, six by the AL - and strikeouts with 34, 17 apiece.
Florida Marlins second baseman Dan Uggla, who entered the contest with six errors on the season, set a dubious mark with three miscues in the contest.
Much to the chagrin of the home fans, Boston Red Sox outfielder JD Drew was named the game's MVP. The slugger became the 15th player in All-Star history to homer in his first at-bat, clubbing a two-run blast off Edinson Volquez to knot the score at 2-2 in the seventh.
The Yankee Stadium crowd rose in approval as Drew's blast cleared the fence, but began to boo again as he rounded third and headed toward home.
The AL squad threatened to end the game against Colorado's Aaron Cook in both the 10th and 11th. The junior circuit loaded the bases with no outs in the 10th on pair of errors by Uggla and an intentional walk.
Cook forced three straight groundballs to escape the jam.
Cook caught a break in the 11th when Ian Kinsler was thrown out trying to steal second after a leadoff single, but surrendered a walk to Dioner Navarro and a single to Drew to put runners on first and second.
Young followed with a sharp single to center field. The Pirates' Nate McClouth picked up the ball on the run and fired towards home, where catcher Russell Martin had the plate blocked. Navarro was out, and Cook retired Carlos Quentin to end the threat.
The NL loaded the bases in the 12th, but lefthander George Sherrill came on to strike out Adrian Gonzalez and end the senior circuit's best scoring opportunity.
The NL held a 3-2 lead in the eighth after an unearned run off Red Sox closer Jonathan Papelbon, who was the source of vociferous booing by the Yankee Stadium crowd after an article in a New York newspaper suggested that the Boston closer believed he should get the call over Yankees closer Mariano Rivera in a save situation.
The AL tied the score again in the bottom of the frame, when rookie Evan Longoria lifted a ground-rule double down the left-field line to score Grady Sizemore, who had singled and stolen second base.