Roger Federer's quest for a sixth Wimbledon title gathered pace with an emphatic 6-2 6-2 6-4 win over Guillermo Garcia-Lopez.
The Swiss second seed wrapped up victory in 89 minutes and will take on Philipp Kohlschreiber for a place in the last 16 after the German ousted Ivo Minar in a five-set thriller.
"I thought all the sets were pretty similar, he won the first service game and I broke him in the next," said Federer, neatly summing up the pattern of an underwhelming match. "I thought one end (of the court) was definitely easier to play from."
"I definitely did not want to underestimate him but I think I did well today, I could even try out a few things in the third set. It was solid and that's exactly what I needed today."
"I expected a much harder match because he's been playing well in Eastbourne, he reached the semis over there. And I've played him twice before where I saw he has some good forehands and steady backhand. On grass you never know so I was quite surprised I was able to win so easily today."
World No.4 Novak Djokovic had little trouble overcoming unseeded German Simon Greul in their second-round clash on Court One.
The 7-5 6-1 6-4 victory sees the fourth seed surpass his previous performance at the All England Club when he was defeated at the same stage last year by Marat Safin.
The Serbian followed up his first round victory over Julien Benneteau with a more assured display against Greul to set up a third-round meeting with American Mardy Fish.
Serve and volley specialist Fish, seeded 28, overcame Serbian Janko Tipsarevic 6-4 3-6 6-1 6-4 in an entertaining match on Court Two.
Spanish seventh seed Fernando Verdasco was made to work before he prevailed a 7-6 6-7 7-6 6-4 victor over Belgium's Kristof Vliegen.
Verdasco, who is ranked 74 places higher than his Belgian opponent, was taken to three tie-breaks before eventually prevailing in four sets.
Australian Open semi-finalist Verdasco will face compatriot and 32nd seed Albert Montanes - a 6-4 6-3 4-6 6-3 winner over Guillermo Canas - in the third round.
No.9 seed Jo-Wilfried Tsonga was earlier the first player to reach the third round of Wimbledon after last 64 opponent Simone Bolelli withdrew through injury.
French No.2 Tsonga, who reached the final of the Australian Open in 2008, will face Croatian 22nd seed Ivo Karlovic after he saw off Steve Darcis, for a place in the last 16.
Germany's Rainer Schuettler was the first male seed to crash out at the second hurdle. The No.18 seed and 2008 semi-finalist was blown away in straight sets by Israel's Dudi Sela 7-6 6-3 6-2.
The reward for Sela's victory is a third-round clash with No.15 seed Tommy Robredo.
The Spaniard produced an inspired comeback to fight back from two sets down to outlast Austrian Stefan Koubek 3-6 4-6 6-4 7-6 6-1 in a marathon second-round clash.
Unseeded Frenchman Michael Llodra was forced to quit his second-round match against Tommy Haas after a heavy collision with a ball girl.
Llodra required medical attention and had to retire from the match at 4-3 behind in the first set, allowing Germany's 24th seed Haas to advance to the last 32.
Marin Cilic will be the German's opponent in the next round after he secured a 4-6 7-6 6-3 6-7 6-4 victory over Sam Querry in the last men's singles match to finish on Wednesday night.
French Open finalist Robin Soderling was a winner as he defeated Marcel Granollers in four sets and he will now face Nicolas Almagro, who was made to work hard for a 6-4 7-6 3-6 3-6 7-5 victory against Karol Beck.